Ulcerative colitis, Crohn's disease, rheumatoid arthritis, atherosclerosis, all these diseases have a common factor. All the four diseases can be traced to chronic inflammation. Of the four, ulcerative colitis closely mimics Crohn's disease. Symptoms are very similar and can often be confusing.
There are certain distinctive characteristics that clearly differentiate both. People with Crohn's disease have more sores around the anus than those with ulcerative colitis. To avoid confusion, learn more about ulcerative colitis. Check out the risk factors of developing ulcerative colitis, symptoms and treatment options. Find out why and how postponing a visit to medical expert can worsen the situation and complicate the condition.
Inflammatory bowel disease
Bowel function is an important function of the human body. Typically, in healthy individuals, stool or feces is composed of water, dead and living bacteria, fiber or undigested food, intestinal mucous and sloughed-off lining of the gut. Also, feces are soft enough to pass comfortably. The activity part of good digestion, if normal, can take place once or two times a day.
But for those with ulcerative colitis, bowel function is not normal. This is because the large intestine becomes inflamed and ulcers may develop. The inflammation starts in the last few inches of the large intestine. It is here the feces is stored before it leaves the body.
Symptoms of ulcerative colitis vary depending on the severity of inflammation and location of inflammation. The general symptoms are bloody diarrhea, rectal pain, urgency in moving bowels, loss of appetite, weight loss, fatigue and night sweats. Medical doctors classify ulcerative colitis based on severity of inflammation and location. There are specific symptoms for each type of classification.
Ulcerative proctitis: This is considered to be the mildest form of ulcerative colitis. The inflammation is limited to the rectum. Symptoms include rectal bleeding with or without rectal pain, a feeling of urgency or an inability to move bowels despite the urge to do so.
Proctosigmoiditis: In this form, both the rectum and the lower end of colon are affected. It can cause bloody diarrhea, abdominal cramps and pain.
Left-sided colitis: True to its name, the inflammation starts at the rectum and extends up the left colon. Symptoms include bloody diarrhea, abdominal cramps, weight loss and left-sided abdominal pain.
Pancolitis or universal colitis: It refers to inflammation affecting the entire colon. Symptoms include bloody diarrhea, abdominal pain and cramps, weight loss, fatigue, fever and night sweats.
Fulminant colitis: Not so common, this is a severe form of pancolitis. Symptoms include dehydration, severe abdominal pain, and protracted diarrhea with bleeding and even shock (a condition where body suffers from insufficient blood flow throughout body).
A unique feature of ulcerative colitis is that the affected individuals may have periods of time with no or some symptoms (called remission) and at times feel acutely sick (called relapse). But, in due course of time, the severity of the disease tends to remain the same. Individuals with milder conditions usually don't go on to develop more severe symptoms.
Ulcerative colitis is most likely to be associated with problems in other parts of the body. The affected individual may suffer from inflammation of the joints, eye problems and anemia due to blood loss.
Ulcerative colitis causes
Medical experts are still clueless regarding exact causes of ulcerative colitis. To a certain extent, there is evidence which suggests that it is a reaction of body's immune system response to a virus or bacteria by causing inflammation in the intestinal wall. This evidence is yet to be proved scientifically. Stress is totally ruled out as a causative factor. Likewise, certain foods or food products cannot be primarily contributing but may set off symptoms.
Certain risk factors identified are:
Age: Problems can develop at any age. Yet, it is most likely to develop between 15-30 years of age or sometimes in people aged 50-60.
Race and ethnicity: Caucasians and people of Jewish ancestry are considered to be at high risk of developing ulcerative colitis.
Heredity: Ulcerative colitis tends to run in families.
Gender: The chances of developing ulcerative colitis in the later part of life i.e. 50-60s are high for men than for women.
Postponing or watchful waiting may only add distress, increase complications, sometimes turn life-threatening and worsen condition. It is best to contact family medical doctor at the earliest. Never ignore periods of recession. If the bowel movements continue to be persistently abnormal, contact medical doctor immediately. Check out for persistent abdominal pain, blood in stool, no respite from bouts of diarrhea in spite taking over-the-counter medications and or fever lasting for a day or two.
Ulcerative colitis diagnosis
Certain question related to understanding patient's medical history will be asked. This will be followed by a complete physical examination checking for signs such as paleness (caused by anemia) and tenderness in the stomach (caused by inflammation). Certain special tests will then be recommended.
Blood tests: Blood tests are conducted to check anemia and high white blood count. In case there is an elevated white blood cell count it reflects ongoing inflammation in the colon.
Stool examination: The stool sample is checked for blood which could mean intestine bleeding. In order to rule out bacterial or viral infection, stool specimens are collected and analyzed.
Colonoscopy or sigmoidoscopy: In order to confirm the diagnosis of ulcerative colitis or to determine the extent of inflammation inside the intestine, colonoscopy or sigmoidoscopy tests are recommended. The procedure is not painful but a sedative is administered to make patient feel relaxed. A long, flexible tube with a camera at the end called an endoscope will be inserted into the anus. The colon and rectum is checked. Inflammation, bleeding, or ulcers on the colon wall is checked. Sometimes, a sample tissue from the lining of the colon may be examined with a microscope.
Barium enema x-ray: The colon is filled with barium, a chalky white solution to facilitate a detailed view of the colon. The test is conducted to check any ulcers or other abnormalities.
Ulcerative colitis treatment
There is no cure for ulcerative colitis. Anti-inflammatory agents play a major role in controlling the symptoms. If the diagnosis confirms the presence of ulcerative colitis, the patient is referred to a Gastroenterologist to assess the severity of the condition and to decide further course of treatment. The Gastroenterologist is likely to ask the patient questions such as:
If the condition is severe, admission to hospital is advised. Otherwise, mild to moderate cases are treated on an out-patient basis. Medical professionals follow two types of treatment of ulcerative colitis.
Managing active ulcerative colitis
Treatment options that don't involve surgery are the first choice.Aminosalicylates, steroids and immunosuppressant are three types of medicines used to manage active ulcerative colitis.
Aminosalicylates: Mostly used to treat mild to moderate ulcerative colitis, aminosalicylates help reduce inflammation. A medicine is also prescribed to relax the patient or relieve pain, diarrhea or infection. Aminosalicylates are available in various forms depending on the severity and extent of the condition. Doctors have the option of prescribing it in oral form as a tablet, a cream to be rubbed into the affected area or as a capsule which should be inserted into the rectum when it can dissolve or a fluid that is pumped into the colon.
Steroids : There are two reasons for steroids to be used. One, if ulcerative colitis is more severe and secondly if aminosalicylates are not effective enough. Steroids are similar to aminosalicylates but are stronger and powerful than aminosalicylates. Steroids are available in form of tablets, cream or suppository or enema. As long term use of oral steroids can cause serious side effects, it must be discontinued as soon as the colitis responds to treatment.
Immunosuppressant: In most cases, immunosuppressant is recommended if the on-going treatment is not effective enough, if steroids have to be withdrawn, to reduce possible side effects of medication. Immunosuppressant may also be used in combination with other medicines.
In order to maintain remission of symptoms, a regular dose of aminosalicylates is prescribed. The symptoms are controlled from recurring. In case the symptoms reoccur on a frequent basis, a regular dose of immunosuppressant is prescribed. However, in case ulcerative colitis is extensive, a lifelong maintenance therapy will be recommended.
Ulcerative colitis surgery
Most cases do not require a surgery. It is an option only when ulcerative colitis does not respond to intensive medical treatment and the condition adversely impacts patient's quality of life. Before any type of surgery, doctors explain details such as:
There are different types of surgery. Most common one is removal of colon and rectum. Removal of the colon is recommended when there is massive bleeding, severe illness, and rupture of the colon and if there is risk of cancer. Waste is rerouted from the colon so that it can pass waste products out of the body.
Another recent technique known as ilio-anal pouch may also be followed. It involves constructing an internal pouch inside the lower abdomen. Waste is collected in the pouch. The pouch is connected to the muscles surrounding the anus. It functions much like the colon.
Coping with ulcerative colitis
The pain, distress, physical discomfort associated with ulcerative colitis can create great emotional stress for the patient. It can lead to depression; make the person feel utterly frustrated, helpless and desperate for support. The role of family is important. Here is information to help the individual.