Epilepsy
Epileptic seizures are commonly traced to brain injury or family history. About 0.5% to 2% of the population is likely to suffer an epileptic seizure at some point in time. When the delicate balance of electrical activity in the brain is disturbed, a person suffers seizures. When there are more than a couple of episodes of seizures, it is a condition of epilepsy. In a typical epileptic seizure, the neuronal activity is hampered bringing on convulsions, muscle spasms and possible loss of consciousness. Each person has a different threshold of resistance to seizures. Inherited condition of neurological disorder can lead to electrical instability causing epileptic seizures. Those dependent on alcohol or drugs may experience seizures during withdrawal. Rarely is a brain tumor the cause of epilepsy. Brain injury is a possible cause of epilepsy. This can be due to a birth defect or head injury or infection such as meningitis. Sometimes a person may experience idiopathic epilepsy where there is no clear cause for the seizures.
Diagnosis of epilepsy can be made with investigative tests such as EEG, CT scan or MRI scan. Anti-epilepsy drugs (AEDs) can control the seizures though there is no cure. These medications help the patient in leading a better quality of life. AEDs are prescribed after studying the person's nature of seizures, general health, age and gender. These medications must be taken in prescribed doses to maintain desired level in the body to prevent further seizures. When some possible triggers have been identified for epileptic seizures, the patient must try and avoid them. These triggers could range from emotional disturbance to lack of sleep. The vagus nerve stimulator(VNS) has been approved by the FDA for the treatment of epilepsy. The VNS is surgically implanted into the chest, near the collarbone. It is a small device, much like a pacemaker that sends weak electrical impulses to the brain through the vagus nerve. These electrical signals are helpful in preventing sudden electrical bursts in the brain that trigger off an epileptic attack.
Seizures
Seizures are conditions when there is abnormal functioning of the brain leading to uncontrollable muscle spasms, altered levels of consciousness and behavior. This is usually traced to abnormal electrical discharge within the brain. Seizures may be localized or affect the whole body.
Seizures are classified into 3 based on the severity of attack and response:
Grand Mal - In this type of seizure, the whole body is racked with convulsions. There can be lack of consciousness or coma
Petit Mal - Only a part of the body is affected by this seizure
Absense - A type of seizure where the affected person is in a stupor and cannot be roused.
Seizures can occur due to poisoning, drug overdose, head injury or medical conditions such as hypoglycemia or neurological abnormality. Fever, brain tumor or other vascular problems can also trigger a seizure. If the brain experiences a sudden lack of oxygen, it can lead to a seizure. Febrile seizures are usually noticed when an infant or small child has high fever, greater than 102 degrees F. The child loses consciousness and experiences uncontrolled shaking of the body. Typically this seizure lasts for a minute or two. Seizures of this kind are not to be mistaken for epilepsy. Though they can be terrifying, febrile seizure attacks must be tackled with care. Place the child on the ground or safe place. Do not restrain movements and wait for the seizure to subside. Do not attempt to feed the child immediately after a febrile seizure. Most seizures are self-limiting. What is essential is to ensure that the person does not get injured during a seizure. Seek seizure first aid. Call a doctor at once if you notice labored breathing or bluish pallor. Epilepsy is a medical condition that is characterized by marked pattern of chronic seizures. Various tests such as spinal tap, heat CT scan or MRI and EEG (Electroencephalogram) can help in identifying the cause for the seizures.
hydromorphone
Indication
A narcotic pain medication used to relieve pain.
Side effects
Sedation, decreased senses, dizziness, seizures, euphoria, low blood pressure, decreased heart rate, nausea, vomiting, constipation, ¯ paralytic ileus, urine retention (cannot void), respiratory depression (slowed breathing), and addiction.
Interactions and precautions
1. Use with alcohol tricyclic antidepressants, sedatives, other narcotic pain medications, antihistamines, muscle relaxants, or other depressants can increase sedation.
2. Use with anticoagulants; (Warfarin) may increase anticoagulant effect.
Usual dose
Adults: oral, 2 mg every three to six hours as needed. Paediatrics: individualized by physician.
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