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Peripheral Vascular Disease

Peripheral Vascular Disease(PVD) or Peripheral artery disease (PAD) is a condition where the arteries supplying blood to the limbs and internal organs get blocked as a consequence of atherosclerosis. Fatty deposits get built up in the arteries and reduce the flow of blood to the organs being supplied by the peripheral arteries. Atherosclerosis is by far the leading cause for Peripheral Vascular Disease. Diabetes is a condition that puts a person at high risk for PVD. Smoking and obesity increases the risk for Peripheral Vascular Disease. Persons who are obese and suffer from hypertension are at higher risk for Peripheral Vascular Disease. A sedentary lifestyle without any exercise should be avoided.

Intermittent claudication is noticed in patients suffering from Peripheral Vascular Disease. Symptoms associated with Peripheral Vascular Disease include numbness or tingling in the limbs, sores that do not heal and pain in the buttocks. A patient suffering from Peripheral Vascular Disease notices changes in skin color and temperature. There may be a dull and cramping pain in the calf, thigh and hip muscles. Ankle Brachial Index (ABI) involves a ratio of the blood pressure in your ankle to the pressure in your arm. Angiogram is a dye test that reveals any possible blockage in the arteries. Ultrasound Doppler Test uses imaging to check for plaque build-up in the arteries. Duplex ultrasound helps in accurate detection of the size of the artery stenosis and the extent of blockage.

Medication is prescribed to eliminate the narrowing of the arteries thereby improving the heart efficiency. Anti-platelet or anti-clotting agents such as cilostazol and pentoxifylline or aspirin and clopidogrel help in improving blood supply to the extremities. Heparin and Warfarin are anticoagulant drugs that can prevent blood clotting. Blood viscocity is controlled to improve blood flow. Drugs to control hypertension and cholesterol may also be prescribed. Bypass surgery allows a new blood route that circumvents the blocked areas of the peripheral arteries. Endarterectomy is a surgical procedure whereby a surgeon cleans out plaque buildup inside the artery of the affected leg or arm. Cryoplasty, a newer form of angioplasty uses liquid nitrous oxide to open a narrowed artery and destroy the plaque within. Regular supervised exercise can reduce symptoms of intermittent claudication.

High Triglyceride

Triglycerides are vital to various cells functions and determine the amount of reserve energy that our body can offer. Triglycerides come from food and are also produced by the body. High blood triglyceride (hypertriglyceridemia) is a lipid disorder. High triglyceride levels are usually accompanied by high total blood cholesterol levels. Blood triglyceride levels are indicative of a person's susceptibility to various diseases such as hypertension, heart attack, cardiovascular disease and atherosclerosis. High levels of triglycerides increase the risk of diabetes and pancreatitis. Blood triglyceride levels of around 150 200 mg/dL are considered normal. While high triglyceride levels are those above 200 mg/dL, those having triglyceride levels greater than 499 mg/dL are at high risk. High triglyceride levels also put a person at increased risk of thrombosis.

Blood triglyceride levels are measured with a blood test after abstaining from food for 12 hours and alcohol for 72 hours before testing. Drugs such as fibrates are often prescribed to reduce elevated levels of triglycerides and cholesterol. Tips to lower triglyceride:

  • Losing excess weight
  • Regular exercise regimen
  • Reducing caloric intake especially fatty foods
  • Restricting alcohol intake
  • Ischemic bowel disease

    Ischemic bowel disease is a medical condition that occurs due to lack of blood flow to the intestines. This disease is seen mostly in older people. If the condition is mild, the disease may improve without treatment. But Ischemic bowel disease can result in an emergency situation in some cases. Ischemic bowel disease results from blocked or narrowed arteries. Tumors or blood clots can be the cause for reduced blood supply. Atherosclerosis is another cause for narrowed arteries.

    Patients suffering form Ischemic bowel disease notice abdominal pain, after eating. There might be rectal bleeding in some cases. Symptoms of ischemic bowel disease include abdominal cramps, nausea and vomiting. The abdomen appears distended and there might be episodes of diarrhea. Certain conditions such as colon cancer, diabetes, congestive heart failure, peripheral vascular disease and sickle cell cancer can increase a person's risk of developing Ischemic bowel disease.

    Diagnosis can be done based on abdomen x-rays and colonoscopy. Angiography of the arteries supplying blood to the bowel helps in detecting the severity of the condition. Antibiotics help in minimizing the infection. Surgery is resorted to in severe cases.