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Uterine Cancer

Uterine cancer manifests in different ways - endometrial cancer and uterine sarcoma. Most instances of uterine cancer occur in the endometrial tissue lining the uterus. While instances of uterine cancer are on the rise, they are curable if detected early. Uterine cancer typically affects a woman after menopause. The noticeable symptoms of uterus cancer is abnormal vaginal bleeding, But not all abnormal bleeding is related to cancer. A doctor can examine the patient and diagnose the condition. Pelvic pain and change in bowel routine are noticed when the cancer of the uterus is at an advanced stage. Certain conditions predispose some women to developing uterine cancer. Obesity is a major factor that increases a woman's risk of developing this disease. Excessive fat cells lead to increased production of estrogen that builds up in the uterine lining. Use of estrogen replacement therapy (ERT) can greatly increase a woman's riks of developing cancer of the uterus. Women who have few or no children and have had a delayed menopause are also at greater risk. Birth control pills containing only estrogen puts a woman at increased risk of uterine cancer. Heredity also plays a role in whether a woman is susceptible to uterine cancer.

A doctor can examine the medical history and conduct a physical examination to check the uterus, vagina, ovaries and rectum. A pap smear is recommended annually for women over the age of 21, especially for those who have been sexually active. A few cells from the cervix and upper vagina are scraped and taken for testing. This test aids in detecting any malignant and pre-malignant changes in the cervix. Uterine cancer is treated with surgery, radiation therapy or chemotherapy or hormones. Often, some of these treatment options are used in combination. Surgery involves removal of uterus and cervix. Chemotherapy involves use of drugs to treat cancer while radiation uses high-intensity rays to kill cancer cells. But women undergoing treatment may experience side effects such as diarrhea, vaginal burning sensation, pain during intercourse, loss of appetite and nausea. Chemotherapy may lead to hair loss, vomiting and drop in blood count.

Breast Cancer

Breast cancer is the second deadliest cancer among women. But it has been noted that with increased awareness and thereby early detection and improved treatment, the number of deaths has reduced. But the incidence of breast cancer has been increasing steadily. Breast cancer is generally noticed in women above the age of 50 years. If a woman has sisters, mother or close blood relatives who have had breast cancer, she is more at risk. Women who have had an early menarche and late menopause are at higher risk for breast cancer. Lifestyle factors such as high alcohol consumption, obesity, diet rich in saturated fat and sedentary lifestyle increases a woman's risk for breast cancer. Long-term use of Hormone Replacement Therapy (HRT) increases the risk of breast cance

Symptoms of breast cancer:

  • Lump or thickening in or near the breast or in the underarm area.
  • Prominently visible veins on the surface of the breast or peeling and scaling should not be ignored.
  • Yellowish green discharge can be a possible breast cancer symptom.
  • Change in size, shape and appearance need to be carefully observed, as it can be a potential symptom of breast cancer.
  • Every woman must learn to conduct a BSE (Breast Self Examination) to check for abnormal lumps, irregularities or discharge from the nipples. Such BSE combined with annual check ups by a doctor improves the chances of detecting breast cancer at an early stage. A Mammogram of the breast is routinely advised for women who are at higher risk for developing breast cancer.

    Appropriate breast cancer treatment is decided on the basis of a number of factors. Breast cancer treatment will depend on a number of factors such as size and location of the breast lump, the stage at which it was detected and the results of hormone receptor tests. Surgery and chemotherapy are often used in combination. Chemotherapy is breast cancer treatment with anti-cancer drugs administered intravenously or orally. This systemic form of treatment is either administered alone or along with surgical procedures. Chemotherapy is a systemic therapy that affects the entire body by entering the bloodstream. This is used widely in breast cancer treatment to interfere with rapidly dividing cells. Radiation is the use of high-energy rays to prevent breast cancer cells from further growth and division. Though normal cells are also affected by this form of breast cancer treatment, they generally repair themselves and function normally afterwards.

    Oncotype DX

    Oncotype DX test measures the levels of specific genes that may indicate the presence of cancer cells. Tbis test helps check the risk of recurence of breast cancer. This test makes use of breast cancer biopsy and studies the patient where the cancer is hormone-receptor positive. Then the Oncotype DX test draws up a recurrence score. A high recurrence score indicates higher chances of cancer recurrence. But this has to be seen along with other factors such as the age of the patient, grade of cancer and size of cancer. This test costs about $3,500. In many cases, the Oncotype DX test helps in deciding whether a woman must go in for chemotherapy and hormonal therapy post surgery for breast cancer. Typically those with low recurrence score may not need to undergo chemotherapy. The Oncotype DX test aids in tailoring treatment to suit the individual needs of each patient.