AFP Test

AFP Test or Alpha-fetoprotein test is conducted on pregnant women to check the AFP level in the blood. The liver in the fetus produces AFP naturally. Determining the amount of AFP in the mother's blood will help identify any neural tube defect in the fetus. Neural tube defects arise in 2 out of every 1,000 pregnancies. AFP test also helps check for Down's syndrome. There are 60% chances for detecting Down's syndrome when the AFP levels are low in the blood. AFP can also be calculated from the sample of amniotic fluid of a pregnant woman. This screening test is generally performed between 16 and 18 weeks of pregnancy and is very sensitive between 15 and 17 weeks. The accuracy of the AFP test result lies in the exact age of the fetus. The AFT test is also referred to as maternal serum alpha-fetoprotein (MSAFP). AFP test is done on men and non-pregnant women too to confirm cancer in the testicles, stomach, pancreas, liver and the ovaries. High levels of AFP can indicate renal cell cancer.

Interpretation of AFP test results: In men and non-pregnant women, the values of the AFP test is 0-6.4 IU/mL (international units per milliliter), 0-20 nanograms per milliliter (ng/mL) or 0-20 micrograms per liter. In pregnant women of about 15 - 22 weeks gestation, the AFP results usually show 19-75 IU/mL, 7-124 ng/mL or 7-124 microgram per liter. AFP test values vary depending on the weight of the woman and race. Black women have higher values than white women and white women have higher values than Asian women. High AFP can suggest multiple pregnancies, fetus with neural tube defects, and abdominal wall defect in the fetus or fetal death. In non-pregnant adults, high AFP values mean cancer in the testicles or ovaries. High AFP can also indicate liver disease and bowel inflammation.

hCG blood test

hCG blood test or pregnancy blood test measures the accurate amount of pregnancy hormone, human chorionic gonadotropin (hCG) in the bloodstream. Pregnancy hormone hCG is produced by the placenta. It can be assessed in the blood and urine of a woman within 10 days of fertilization. hCG can be measured by:

Quantitative pregnancy blood test: This test measures the accurate amount of hCG in the blood of a woman and plays a vital role in assessing the age of the fetus. This test also helps in checking if the pregnancy is developing normally.

Qualitative pregnancy blood test: This test can only tell if there is hCG present in the blood and can give no further information. This test result is like the home based pregnancy test kit just giving a 'yes' or 'no'.

In men and non pregnant women, the typical levels of hCG is less than 5 international units per liter (IU/L). In pregnant women, it is about 5 - 100 during 24 to 28 days after last menstrual period (LMP). During 4 to 5 weeks after the LMP, the hCG is about 50-500 IU/L and peaks to about 12,000 - 270,000 IU/L during 14 - 16 weeks of pregnancy. High levels of hCG can signify multiple pregnancy or molar pregnancy or Down's syndrome. In non-pregnant women and in men, it can signify cancerous or non-cancerous tumor of the testicles or ovaries. Low values of hCG in pregnant women can signify ectopic pregnancy, death of baby or that the pregnancy is not proceeding the way it has to. It can also indicate a spontaneous miscarriage.

L carnitine is an amino acid naturally synthesized by the body from amino acids - Lysine and methionine. This amino acid is found mostly in red meats and in smaller quantities in diary products. As L carnitine is similar to another amino acid Carnitine which plays a major role in energy metabolism. The body produces carnitine in the liver and kidneys and stores it in the skeletal muscles, heart, brain and sperm. Deficiency in these amino acids can manifest as general apathy, fatigue, muscle weakness, decreased tolerance to metabolic stress, and cardiomyopathy.

Symptoms of fatigue and general prognosis improved significantly in those patients who received oral L-carnitine supplementation. L carnitine's action of facilitating the transport of fatty acids is useful in preventing a buildup of amyloid plaque that damages brain tissues. Supplements of L carnitine has helped in some studies, to improve sperm mobility in men with poorly active sperm, a condition known as asthenozoospermia. Some laboratory studies have indicated the beneficial effects of L-carnitine supplements in counteracting the toxic effects of AZT, a drug for the treatment of HIV - human immuno deficiency virus and acquired immuno deficiency syndrome. Cartinine and L-Cartinine are thought to improve some of the following conditions:

• Heart Disease - As Cartinine helps to improve the overall energy levels, the patients have a better sustained physical activities after suitable medications combined with supplements.
• High Cholesterol - Patients with elevated levels of cholesterol and triglycerides reported a significant lowering.
• Intermittent Claudication - Patients with Deficiency in blood circulation in the peripheral regions ( peripheral vascular disease PVD ) reported better muscle functions after taking supplements.
• Fatty Liver - Alcohol induced fatty buildup in the liver has been reversed and even prevented in some studies.
• Down's Syndrome - In patients afflicted with this disease, significant improvement in visual memory and attention span was noted after supplements.
• Male Infertility - supplementation may increase sperm count and Sperm mobility.